Publication Announcements

Review of Massively Parallel MicroRNA Profiling in Cancer

Massively Parallel MicroRNA Profiling in the Haematologic Malignancies

Profiling model T cell metagenomes

Profiling model T cell metagenomes with short reads.

cisRED C. elegans conserved element database

Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements

Macroautophagy: The key ingredient to a healthy diet?

Macroautophagy: The key ingredient to a healthy diet?

An executioner caspase regulates autophagy

An executioner caspase regulates autophagy

Drosophila Genes Involved in Programmed Cell Death

Characterization of Drosophila Genes involved in Programmed Cell Death

Non-linear Electrophoretic Response Yields a New Parameter for Separation of Biomolecules

This paper was just accepted for publication in PNAS. It describes a novel and highly efficient electophoresis method for isolation and purification of DNA. The proof of principle application described in the paper was the isolation of DNA from a drilling core from the Athabasca oil sands, which was subsequently subjected to metagenomic sequencing and analysis here at the GSC.

Circos: An information aesthetic for comparative genomics.

Visualization system for comparative genomics.

The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

Next generation tag sequencing for cancer gene expression profiling

Profiling the T-cell Receptor Beta-chain Repertoire by Massively Parallel Sequencing

Determining Potential Virulence Factors from the Protozoan Parasite Leishmania donovani

Proteomic analysis of the secretome of Leishmania donovani.

A novel method for the analysis of Serial Analysis of Gene Expression (SAGE) data

A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data.

Synthetic genomes brought closer to life.

Synthetic genomes brought closer to life.

Common regulators between autophagy and cell death

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis

Bacterial transcription

Transcription of foreign DNA in Escherichia coli

Previously unknown genes have been found through SAGE analysis in androgen independent prostate cancer.

Novel expressed sequences identified in a model of androgen independent prostate cancer.

H2AFX and Non-Hodgkin Lymphoma

Genetic variation in H2AFX contributes to risk of non-Hodgkin lymphoma.

Development of a Meta-Analysis Method to Rank Colorectal Cancer Biomarkers

Meta-analysis of colorectal cancer gene expression profiling studies identifies consistently reported candidate biomarkers.

H3K4me1, H3K4me3 and transcription factor binding.

Genome wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding.