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Scientific Publications

Search results for "Leach S"

2017/02/11

Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.

Several studies have found that long-lived individuals do not appear to carry lower numbers of common disease-associated variants than ordinary people; it has been hypothesized that they may instead c...

2013/05/28

Shift work, circadian gene variants and risk of breast cancer.

Circadian (clock) genes have been linked with several functions relevant to cancer, and epidemiologic research has suggested relationships with breast cancer risk for variants in NPAS2, CLOCK, CRY2 an...

2013/03/19

Genetic polymorphisms at TIMP3 are associated with survival of adenocarcinoma of the gastroesophageal junction.

The poor survival of adenocarcinomas of the gastroesophageal junction (GEJ) makes them clinically important. Discovery of host genetic factors that affect outcome may guide more individualized treatme...

2012/11/15

Catenin Family Genes Are Not Commonly Mutated in Hereditary Diffuse Gastric Cancer.

BACKGROUND: Approximately one third of the hereditary diffuse gastric cancer (HDGC) families carry germline mutations in the E-cadherin gene (CDH1). Risk prediction in members of families with this ra...

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