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The Canadian Pediatric Cancer Genome Consortium: Translating next-generation sequencing technologies into improved therapies for high-risk childhood cancer.

Characterizing pediatric cancers through comprehensive genome review. Using the genetic information to find new therapies.

Project Leaders Poul Sorensen
Project Co-Investigators Michael Taylor , Cynthia Hawkins, Nada Jabado, David Malkin, Annie Huang, Conrad Fernandez
Involved Organizations
Funding Agencies
Children having fun in park from Getty Images.  Photographer: Vyacheslav Osokin. Copyright.

CPCGC: improving cancer outcomes.


Cancer is the most common cause of non-accidental death in children and remains an unacceptable socioeconomic burden for Canada and Canadian families. A considerable proportion of childhood cancers remain incurable or can only be cured with treatments that leave a child with life-long mental or physical disabilities.

The aim of this project is comprehensively interrogate the genomes of four pediatric cancers and possibly discover new targets for therapy for these devastating diseases.

A group of highly accomplished Canadian researchers and clinicians who are experts in childhood cancer and novel DNA sequencing technologies are using “next generation sequencing technology” to scan the entire genomes of each of four of the most challenging childhood cancers known. They will directly compare the genetic code of primary tumour cells and tumour cells that have spread, or relapsed, in medulloblastoma, osteosarcoma, diffuse instrinsic pontine glioma and atypical teratoid Rhabdoid tumour. Thereby uncovering the genetic abnormalities that allow tumour cells to spread or become resistant to treatment.

Recent Publications:

Contact Details

For all project related inquires please contact us.

Karen Novik, Project Manager
Genome Sciences Centre, BC Cancer Agency
Phone: 604-675-8000 x 7983
Alla Sekunova, Projects Coordinator
Genome Sciences Centre, BC Cancer Agency
Phone: 604-675-8000 x 7977