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MiRNA Profiling
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ORegAnno: Open Regulatory Annotation
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SNVMix
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SliderII
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Chinook
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Circos
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CORAL (Contig Ordering Algorithm)
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DiscoverySpace
Releases
DiscoverySpace poster
Roadmap
FASSI - Fingerprint and Assembly Incorporation
Releases
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FindPeaks
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GUM: Group, User Manager
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Internet Contig Explorer (iCE)
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SAM - Sequence Assembly Manager
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SAM Powerpoint presentation
Slider
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Sockeye
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SSAKE
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THOR
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Trans-ABySS
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TreeBuilder3D
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XMatchView
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pRHL1 Vs. pRHL2
Alignment between C. gattii strain WM276 and B3501
Repeats on D. melanogaster
Repeats within U. hordei mating locus
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Documentation
DiscoverySpace Primer
DiscoverySpace Scatter Plot
DiscoverySpace tutorial (Mouse Atlas project)
SAGE
General
Query Primer
DiscoverySpace Template Primer
DiscoverySpace Databank Primer
Resources
Gene Ontology (GO)
resources
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LaneRuler Documentation
JAGuaR
JAGuaR poster
Documentation
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Drug Discovery
Proteomics
Proteomics Research
Sequencing
Solid
Illumina HiSeq
Illumina Sequencing
Illumina HiSeq 2000
Illumina HiSeq 2000
Sequencer Panorama
Platforms
Publications
Publications 2010
Scientific Publications
DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma.
Clonal evolution of high-grade serous ovarian carcinoma from primary to recurrent disease.
MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition
Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression.
Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma.
Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling.
BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data.
Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II.
Beta-catenin expression is prognostic of improved non-small cell lung cancer survival.
Hemithyroidectomy is the preferred initial operative approach for an indeterminate fine needle aspiration biopsy diagnosis.
Allelic ratios and the mutational landscape reveal biologically significant heterozygous SNVs.
Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target.
Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors.
Feature-based classifiers for somatic mutation detection in tumour-normal paired sequencing data.
GPSM2 mutations cause the brain malformations and hearing loss in Chudley-McCullough syndrome.
Subgroup-specific alternative splicing in medulloblastoma.
DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution.
Mutations in EZH2 cause Weaver syndrome.
Targeting autophagy: The Achilles' heel of cancer.
Estimation of rearrangement phylogeny for cancer genomes.
Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.
Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer.
Comprehensive genomic characterization of squamous cell lung cancers.
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.
Identification and characterization of Hoxa9 binding sites in hematopoietic cells.
Inhibition of glutamine-dependent autophagy increases t-PA production in CHO cell fed-batch processes.
Transcriptome and full-length cDNA resources for the mountain pine beetle, Dendroctonus ponderosae Hopkins, a major insect pest of pine forests.
Guidelines for the use and interpretation of assays for monitoring autophagy.
Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer.
Here, there be dragons: charting autophagy-related alterations in human tumors.
14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma.
The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD).
Drug repositioning for personalized medicine.
Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
Genome-wide association study for ovarian cancer susceptibility using pooled DNA.
Recurrent targets of aberrant somatic hypermutation in lymphoma.
Use of mutation profiles to refine the classification of endometrial carcinomas.
Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity.
Next-generation sequencing of prostate tumors provides independent evidence of xenotropic murine leukemia virus-related gammaretrovirus contamination.
Large scale phosphoproteome analysis of LNCaP human prostate cancer cells.
Barriers to integrating personalized medicine into clinical practice: a best-worst scaling choice experiment.
Points of view: Managing deep data in genome browsers.
Points of view: Representing the genome.
Points of view: Representing genomic structural variation
Spark: A navigational paradigm for genomic data exploration.
PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium.
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples.
Inhibition of COX-2 in colon cancer modulates tumor growth and MDR-1 expression to enhance tumor regression in therapy-refractory cancers in vivo.
Metagenomic and Metabolomic Characterization of Rabies Encephalitis: New Insights into the Treatment of an Ancient Disease.
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.
JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data.
Advances in small molecule inhibitors of androgen receptor for the treatment of advanced prostate cancer.
Catenin Family Genes Are Not Commonly Mutated in Hereditary Diffuse Gastric Cancer.
Genetic variation in cell death genes and risk of non-Hodgkin lymphoma.
TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma.
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Coordinated expression of galectin-3 and caveolin-1 in thyroid cancer.
Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.
The Autophagy Protein LC3A Correlates with Hypoxia and is a Prognostic Marker of Patient Survival in Clear Cell Ovarian Cancer.
A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.
Life-history chronicle for a patient with the recently described chromosome 4q21 microdeletion syndrome.
Correlation of clinical response and response duration with miR-145 induction by lenalidomide in CD34+ cells from patients with del(5q) myelodysplastic syndrome.
Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse.
Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer.
Poly-gene fusion transcripts and chromothripsis in prostate cancer.
Ab initio parameterization of YFF1, a universal force field for drug-design applications.
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.
Dissect: detection and characterization of novel structural alterations in transcribed sequences.
Bromodomain-Containing-Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells.
Comprehensive molecular characterization of human colon and rectal cancer.
Comprehensive molecular portraits of human breast tumours.
Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development.
The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.
Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null mice.
Absence of NR2E1 mutations in patients with aniridia.
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage.
Derivation of HLA types from shotgun sequence datasets.
Dissect: detection and characterization of novel structural alterations in transcribed sequences.
MotifOrganizer: a scalable model-based motif clustering tool for mammalian genomes .
Notch-Dependent Regulation of the Ischemic Vasodilatory Response--Brief Report.
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.
Comprehensive molecular characterization of clear cell renal cell carcinoma.
Complete genomic landscape of a recurring sporadic parathyroid carcinoma.
Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.
Distinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cells.
The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and a comparison with the bark beetle-associated pine pathogen Grosmannia clavigera.
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
Identifying cancer mutation targets across thousands of samples: MuteProc, a high throughput mutation analysis pipeline.
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape.
Genetic polymorphisms at TIMP3 are associated with survival of adenocarcinoma of the gastroesophageal junction.
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
Assembling the 20 Gb white spruce (Picea glauca) genome from whole-genome shotgun sequencing data.
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Brain microbial populations in HIV/AIDS: α-proteobacteria predominate independent of host immune status.
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma.
Notch activation promotes endothelial survival through a PI3K-Slug axis.
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species
SASH1 Is a Scaffold Molecule in Endothelial TLR4 Signaling.
The shaping and functional consequences of the microRNA landscape in breast cancer.
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition..
Shift work, circadian gene variants and risk of breast cancer.
Transcriptome resources and functional characterization of monoterpene synthases for two host species of the mountain pine beetle, lodgepole pine (Pinus contorta) and jack pine (Pinus banksiana).
The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and a comparison with the bark beetle-associated pine pathogen Grosmannia clavigera.
Epigenomics: sequencing the methylome.
Integrated genomic characterization of endometrial carcinoma.
Complete genomic landscape of a recurring sporadic parathyroid carcinoma.
Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins, a major forest pest.
Points of view: Elements of visual style.
Points of view: Labels and callouts.
Points of view: plotting symbols.
A handheld electromagnetically actuated fiber optic raster scanner for reflectance confocal imaging of biological tissues.
The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma.
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing.
Cancer genome-sequencing study design.
An androgen receptor N-terminal domain antagonist for treating prostate cancer.
A cancer stem cell model for studying brain metastases from primary lung cancer.
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
The genetic landscape of high-risk neuroblastoma.
Shared genetic factors for age at natural menopause in Iranian and European women.
Using high frequency Raman spectra for colonic neoplasia detection.
Analysis of FOXO1 mutations in diffuse large B-cell lymphoma.
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods.
Correlation of clinical response and response duration with miR-145 induction by lenalidomide in CD34(+) cells from patients with del(5q) myelodysplastic syndrome.
A Phosphoproteomics Approach to Identify Candidate Kinase Inhibitor Pathway Targets in Lymphoma-Like Primary Cell Lines.
Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.
Genome-wide microRNA and messenger RNA profiling in rodent liver development implicates mir302b and mir20a in repressing transforming growth factor-beta signaling.
Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence.
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape.
Spongian diterpenoids inhibit androgen receptor activity.
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
RNA-Seq Analysis of Gene Expression, Viral Pathogen, and B-Cell/T-Cell Receptor Signatures in Complex Chronic Disease.
Kollector: transcript-informed, targeted de novo assembly of gene loci.
Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.
Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.
Genetic Polymorphism at BCL2 as a predictor for R-CHOP efficacy in patients with diffuse large B-cell lymphoma.
Non-Genomic Actions of the Androgen Receptor in Prostate Cancer.
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer.
Tumor potentiating mechanisms of Fusobacterium nucleatum, a multifaceted microbe.
Cell-Based Therapeutics: Making a Faustian Pact with Biology.
Integrated genomic and molecular characterization of cervical cancer.
Characterization of treatment and outcomes in a population-based cohort of patients with chronic lymphocytic leukemia referred for cytogenetic testing in British Columbia, Canada.
ntCard: A streaming algorithm for cardinality estimation in genomics data.
Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Integrated genomic characterization of oesophageal carcinoma.
Innovations and challenges in detecting long read overlaps: an evaluation of the state-of-the-art.
Defining the clonality of peripheral T cell lymphomas using RNA-seq.
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.
Combined oral contraceptive use before the first birth and epithelial ovarian cancer risk.
Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study.
Sequencing Strategies to Guide Decision Making in Cancer Treatment.
Genome-wide chemical mapping of O-GlcNAcylated proteins in Drosophila melanogaster.
Projects
Mouse Atlas
Images
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Mouse Atlas of Gene Expression Summary
Mouse Atlas Research Teams
SAGE Team
Mouse Team
Bioinformatics Team
Healthy Aging Study
Publications for download
Analysis of long-lived C.elegans, 2005
Telomere length in the healthy oldest old, 2008
Genetic Variation in Healthy oldest-old, 2009
Progeria of stem cells, 2007
Healthy Seniors
Healthy Seniors
Bovine Genome Sequencing
Sequence Files
FL cDNA Seqs - Zipped Sept 13
Readme
Bovine Full-length cDNA Sequencing
Calfs
Expression Profiles of Cells and Tissues in C. elegans
Treenomix: Spruce, Poplar and Arabipdopsis
Forestry Genomics Summary
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Functional Genomics of C. Neoformans
Cryptococcus Neoformans Summary
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Atlantic Salmon
Atlantic Salmon Summary
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Cancer Genomics
Cancer Genomics Summary
Microbial Envirogenomics
Rhodococcus Summary
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Bioinformatics of Mammalian Gene Expression
Chinook
Documentation
ChinookAutoConfGuide.pdf
chinook-bugs-nov-24.pdf
CUD-Adding_New_Services.pdf
CUD-Chinook_Advertisements.pdf
CUD-Creating_JBuilder_Chinook_Environment.pdf
CUD-Intro_Chin_Packages_and_Ext_Dirs.pdf
CUD-Running_Chinook_Node.pdf
Images
Screenshots
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Algorithms accessible via Chinook
Chinook Screenshots
Chinook Download
Chinook Mailing Lists
Chinook Documentation
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Chinook Platform Overview
user_guide
Coexpression
Supplementary Materials
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javaws.js
javaws.vbs
Sockeye
Images
Screenshots
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movies
Sockeye How-To Movie (Alignment)
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Algorithms currently supported by the Sockeye Platform (through Chinook)
Sockeye Screenshots
Sockeye Documentation
Sockeye FAQ
What Can Sockeye Do
Sockeye 1.3 Release Note
What's New in Sockeye 1.2
Sockeye Credits
Bibliography
Sockeye Mailing Lists
Sockeye Immediate Help
Sockeye Collaborations
Sockeye 1.2 Release Note
What's New in Sockeye 1.3
Sockeye
Sockeye Download
Sockeye historical releases
Sockeye 0.8.2 Release Notes
Sockeye Version 1.0 User’s Guide
Sockeye Version 1.0 User’s Guide
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Lay Summary
ENCODE Target Regions
Gene Regulation (Informatics)
SARS Sequencing
SARS
SARS clones
TOR2_genome_shotgun_120403.fasta.gz
clone_list.pdf
TOR2_draft_genome_assembly_120403.fasta
TOR2_finished_genome_assembly_290403.fasta
Mammalian Organogenesis (MORGEN)
whitemice
Pleiades Promoter Project
High Resolution Analysis of Follicular Lymphoma Genomes
Ribbon model of EZH2 polymorphisms.
EZH2 ribbon model
Follicular Lymphoma as a Model of Cancer Progression
Mutation Specific Inhibitors in Breast Cancer Cell Lines
Mutation specific icon
Genomics of Berry Quality in Grapevine (GrapeGen)
Canadian Molecular Cytogenetics Platform
Genomic Tools for the Diagnosis and Evaluation of Mental Retardation
Development of Technologies for the Derivation, Propagation and Differentiation of hESC
Identification and Cloning of deletions in C. elegans.
Mammalian Gene Collection - Closure (MGC)
Autophagy and Apoptosis Crosstalk
InCell Analyzer LC3 Drosophila
Role of Autophagy in the Therapeutic Response of Breast Cancer Cells
Colorectal Cancer Screening
Anatomical Model showing the human colon
CIHR Team
Potential Therapy for Prostate Cancer
Potential Therapies
Tumor infiltrating T cells in Ovarian Cancer
Rosettes of dividing T-cells
Lymphoma Transcriptome Sequencing and Analysis
karyotype
EZH2 mutations
Single Cell Genomics
Empty chip
Microfluidic Chip Prototype
Genetic Analyses of Lymphoid Neoplasms
lymphoid-neoplasm
Terry Fox Foundation
Genetics of Non-Hodgkin Lymphoma
Lymphoma Families Study
Example family tree with Lymphoid cancers indicated as solid shading.
Genetics of Aortic Valve Stenosis
Heart Diagram
Massively Parallel Sequencing of the human T-cell Receptor Repertoire
Massively Parallel Sequencing
Images
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Discovery of new drug candidates for the clinical management of prostate cancer
Androgen Receptor DNA-binding-domain
Screening Robot
The Cancer Genome Atlas (TCGA)
TCGA
TCGA Logo
Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)
CIRM - HALT
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Investigating Autophagy Proteins as Molecular Targets for Cancer Treatment
Atg4B active site topography
Atg4B (gray) and LC3 interaction model.
Lymphoid Cancer Families Study
Recruitment for Lymphoma Study
Lymphoid Cancer Families Study
Recruitment for Lymphoma Study 2013
Lymphoma Families Recruitment 2016
Roles of macroautophagy in Drosophila development
MAGIC - Medulloblastoma Advanced Genomics International Consortium
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The Brain
Centre for Epigenome Mapping Technologies (CEMT)
Schematic of a nucleosome - a unit of chromatin
The Canadian Pediatric Cancer Genome Consortium (CPCGC)
CPCGC Project
CPCGC: improving cancer outcomes.
Personalized Oncogenomics
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Scientific Publications from the Personalized Oncogenomics study
A Terry Fox New Frontiers Program Project Grant: Exploiting Pathogenic Mechanisms in Acute Leukemia for Clinical Translation
Terry Fox logo
Terry Fox New Frontiers research team
POG
Data
Bovine
High Resolution Analysis of Folicular Lymphoma
Pleiades
Pleiades
Data Release Policy: Open Access
Thyroid
Training
Services
Bioinformatic Services
Sequencing Services
Ilumina Sequencing
Using sFTP to access Illumina sequence data
Sequencing data access using sFTP
Duplex UMI
Alert Text Table
Sequencing Libraries - FAQ
Frequently Asked Questions
FAQ 2018 Document
Terms of Service
Statement of Work Terms and Conditions
ORCA
ORCA
LIMS: Lab Submission
Faculty
Dr. Marco Marra, OBC, PhD, FRS(C), FCAHS
Introduction to the Genome Sciences Department and the Genome Sciences Centre
Honors and Awards
Marra Research Activities
Trainee Projects
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Titles and Education
Dr. Steven Jones, PhD, FRSC, FCAHS
Dr. Robert Holt, PhD
Dr. Martin Hirst, PhD
Dr. Gregg B. Morin, PhD
Dr. Angela Brooks-Wilson, PhD
Dr. Sharon M. Gorski, PhD
Dr. Aly Karsan, MD, FRCPC
Dr. Inanc Birol, PhD
Dr. Marianne Sadar, PhD
Dr. Ryan D. Morin, PhD
Dr. Isabella T. Tai, MD/PhD, FRCP(C)
Research Interests
Education
Lab Members
Group Photos of Tai Lab Members
2004 Lab Members
2005 Lab Members
2006 Lab Members
2007 Lab Members
Members of 2007 (1)
Members of 2007 (2)
Members of 2007 (3)
2008 Lab Members
Members of 2008 (1)
Members of 2008 (2)
Members of 2008 (3)
Members of 2008 (4)
2009 Lab Members
Members of 2009 (1)
2010 Lab Members
Members of 2010 (1)
2011 Lab Members
Members of 2011 (1)
Members of 2011 (2)
Members of 2011 (3)
2012 Lab Members
Members of 2012 (1)
Members of 2012 (2)
2013 Lab Members
Members of 2013 (1)
Members of 2013 (2)
Members of 2013 (3)
Members of 2013 (4)
2015 Lab Members
Members of 2015 (1)
Members of 2015 (2)
Members of 2015 (3)
2016 Lab Members
Members of 2016 (1)
2017 Lab Members
Members of 2017 (1)
Members of 2017 (2)
Publications Complete
Dr. Nadine Caron, MD
Careers
Research Assistant 2, Proteomics
Assistant Bioinformatics Coordinator, Software Development
Manager, Employee Relations, GSC
Research Programmer – Microservice Developer
Post-doctoral Fellow in the proteomic discovery of immunotherapy
Research Associate, Precision Genomics for Cancer
Research Associate
Staff Scientist 2
Research Programmer (Web Development)
About
Funding Support
BC Cancer Foundation
BC Cancer
CGEn
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News Releases
Widespread News coverage of Breast Cancer discovery published in Nature.
BC Cancer Agency lymphoma discovery
FASSI 0.1 released
Mouse Atlas of Gene Expression web site launched
Draft genome sequence for the fungal pathogen Cryptococcus neoformans variety gattii released
Almost Human
Internet Contig Explorer version 3
Mouse Atlas of Gene Expression project funded by Genome Canada
Minister Allan Rock and new CEO for Genome BC announce completion of BC genomics research agreements
Minister of Health Visits the GSC
Ensembl Mirror
New BC Cancer Research Centre Launch
Training Program in Bioinformatics
BC Cancer Foundation to receive $10M for genome research
Posters: Genome Sciences Centre at BCCA Annual Conference 2002
Mouse Physical Map Completed
BC genomics researchers receive new approvals bringing funding to over $100 million
Bioinformatics of Mammalian Gene Expression project funded by Genome Canada
Minister of Industry Tours the GSC Facilities
National Post Feature
DiscoverySpace 3.2.1 update adds SAGE tag mapping
Signs of Aging
First multi-species build of regulatory element database available
Sockeye 1.2 Released
C. elegans nematode SAGE data
The Anniversary of the Helix
Sockeye 1.1 Released
Canadian Foundation for Innovation Announces $27.8 Million for BC Cancer
Human CGH BAC Rearray
Genome Sequence Centre Completes a Physical Map of the Mouse Genome
Provincial Government Funding
Tzu Chi Foundation joins BC Cancer Foundation in unlocking the mysteries of cancer
Cancer Research Centre Gets Knowledge Development Funding
Posters: Genome Sequencing & Biology at CSHL 2002
Worming Our Way to a Longer Life
OSCAR 4.0 Released
Human regulatory element database released
Posters: Advances in Genome Biology and Technology (AGBT) 2003
Draft genome sequence for Rhodococcus RHA1 published
Sockeye 1.2 Beta Released
Sockeye 0.8.2 Released
GSC Bioinformatics platform is moving
Chinook Honoured
Bovine Genome Sequencing Project
SARS Associated Coronavirus
Sockeye 1.0 released
cisRED database paper accepted for publication in NAR
Open Regulatory Annotation Database Released
ORegAnno hits 3000 records
ORegAnno adds UCSC genome browser track
Regulatory module update in human and mouse cisRED databases
New Epigenomics Initiative
Genome Science and Technology Program
2010 Genome BC Award for Scientific Excellence
BC Scientists develop new drug candidate for prostate cancer
Personalized genome sequencing in cancer treatment—a major breakthrough in care
Marco Marra, one of fifteen new members of the Order of British Columbia
OvCaRe Researchers reveal a major new cancer gene - ARID1A
OvCaRe Researchers
Dr. Sarah Finlayson, gynecologic oncologist with BCCA, and Dr. David Huntsman are interviewed by media at the Sept. 8th ovarian press conference. Photo courtesy of Cameron Heryet.
Interdisciplinary Cancer Control for the 21st Century - BC Cancer Agency’s Annual Cancer Conference
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BC Cancer Agency Annual Conference Recognition Awards
Dr. Marco Marra awarded a Tier 1 Health Canada Research Chair in Genome Science
International Human Microbiome Congress
International Human Microbiome Congress
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The Canadian Pediatric Cancer Genome Consortium
Canadian Institutes of Health Research
Genome BC
Genome Canada
Genome BC
C17
Meulien and Goodyear
Genome Quebec
Autophagy Symposium - March 25th
Canadian Institutes of Health Research
CDRD
MSL
UBC
BCCA-GSC
Personalized Medicine on the Horizon for BC Cancer Patients
Michael Smith Genome Sciences Centre
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BC Cancer Foundation
Personalized Medicin Launch
Dr. Aly Karsan
Dr. Alan Winter
BC Cancer Agency Annual Conference - call for Abstracts
Poster Session 2010
Gene Screen BC video competition
2012 AAAS Annual Meeting from 16-20 February in Vancouver, B.C.
Video of Dr. Marianne Sadar speaking at the IMPaCT Meeting Plenary session
Government of Canada Strengthens Cancer Research in British Columbia
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Marianne Sadar
BC Cancer Agency and Dana-Farber Cancer Institute research teams independently identify first infectious agent associated with colon cancer
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Steven J.M. Jones honoured as a Fellow of the Royal Society of Canada
The Cancer Genome Atlas (TCGA) 1st Annual Scientific Symposium: presentations on-line
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Lloyd Skarsgard Excellence in Research Award 2011
Dr. Skarsgard and Ryan Morin
Dr. Skarsgard and Ryan Morin
Autophagy Workshop & Symposium 2012
Michael Smith Distinguished Research Lecture - April 10th
The Centre for Clinical Genomic Diagnostics (CDG) gains CAP accreditation
Darwinian evolution in the deadliest of breast cancers
TCGA Researchers Report on Colorectal Cancer Analyses
MAGIC - Medulloblastoma Advanced Genomics International Consortium discover subgroups in childhood brain cancer
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The Eleventh Asia-Pacific Bioinformatics Conference (APBC2013) Vancouver
Worksafe BC award for Innovation in Ergonomics won by GSC Engineers
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January 21 -23rd Asia-Pacific Bioinformatics Conference (APBC2013) Vancouver
Researchers at the BC Cancer Agency part of global initiative to understand the human “epigenome”
The Super Seniors Study featured by the Canadian Cancer Society
Centre for Clinical Genomics successful in CAP accreditation renewal
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Award presented by the Swiss Institute of Bioinformatics for ABySS software
New cancer-fighting funds to help patients with aggressive non-Hodgkin lymphoma
The Terry Fox New Frontiers Program Project Grant in Core Pathogenic Pathways in Human Leukemia funds Dr. Martin Hirst
The 14th Human Proteome Organization World Congress - Vancouver 2015
Dr. Marco Marra recipient of the Faculty of Medicine’s Dr. Chew Wei Memorial Prize in Cancer Research.
2015 Skarsgard Awards Presented
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K. Rothe
Containerized bioinformatic analysis platform 'ORCA' launched
Genomic Medicine Canada 2017 - March 1, 2017 Meeting Announcement
CGEn awarded MSI funding for 2017-2022
Canada's Genomics Enterprise logo
Flow Cell
"Cracking Cancer" on The Nature of Things with David Suzuki, CBC
BC scientists play major role in international effort to map the human epigenome
Northern biobank will fill health knowledge gaps in rural, First Nations communities
The Centre for Clinical Genomics (CCG) successfully accredited by the College of American Pathologists (CAP).
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Dr. Sharon Gorski receives 2017 Neuroendocrine Tumor Research Foundation – American Association for Cancer Research (AACR)
BC Cancer Agency Report to the Community 2016 now available online
BC Cancer Agency Report to the Community 2016 Cover Page
Registration now Open - Vancouver Autophagy Symposium 2017
4th Canadian Conference on Epigenetics: Mechanisms of Disease - Whistler, British Columbia from November 26-29, 2017
GSC Video from ASHG-TV
Beluga Genome Sequencing
Generation of Native Chromatin Immunoprecipitation Sequencing Libraries for Nucleosome Density Analysis
2 Petabase Goal Reached
Sequencing to Date
Genomics education resources now available on POG website
GSC scientists sequence the grizzly bear genome
Dr. Ryan Morin receives 2019 American Society of Hematology Scholar Award
The GSC is now ISO 27001 certified
Uncovering antibiotics and cancer drugs in bullfrog DNA
New study uses artificial intelligence, whole genome sequencing to make accurate cancer diagnoses
Steller sea lion genome sequenced
Dr. Steven J.M. Jones appointed Canada Research Chair for Computational Genomics
Scientists enhance important tool used to research the deadliest form of brain cancer
A genetic explanation for lymphoma patients that cannot be cured by standard treatment
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BC Premier John Horgan visits the GSC
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Scientists develop a new method for finding cancer-killing cells
Publication Announcements
"ABySS-Explorer: Visualizing Genome Sequence Assemblies"
De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data
Genetic variants associated with susceptibility to FL
The completion of the Mammalian Gene Collection (MGC)
The iSSAKE short read sequence assembly approach for profiling T cell metagenomes
Visualization system for comparative genomics.
Predicted mutational epitopes suitable for immunological cancer control
De novo assembly of a fungus genome
A review of techniques for the detection of genome rearrangements in tumor genomes.
Whole Transciptome Shotgun Sequencing
Development of a Meta-Analysis Method to Rank Colorectal Cancer Biomarkers
Profiling miRNA expression in human stem cells using next-generation sequencing
Synthetic genomes brought closer to life.
Nucleic Acids Research Publication 2008
New software for genetic analysis
Optimal pooling of BACs for genome re-sequencing
Determining Potential Virulence Factors from the Protozoan Parasite Leishmania donovani
Mitochondrial genome redundancy in two dinoflagellates
Software for CNV analysis using Affymetrix SNP arrays
SPARC enchances apoptosis via caspase 8
Computational platform for splicing microarray design
ChIP-seq for STAT1 in HeLa cells
Method to detect and classify genome rearrangements
Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells
Transcriptome profiling of Caenorhabditis elegans in its first larval stage
Rebuilding microbial genomes
Investigation of molecular markers of lung cancer to predict drug response
Open regulatory annotation database released.
Understanding Gene Control
Bacterial transcription
A physical map for the poplar tree genome
Study finds genomic properties for the detection of rSNPs
A review of novel applications of next-generation sequencing technologies
A novel method for the analysis of Serial Analysis of Gene Expression (SAGE) data
H3K4me1, H3K4me3 and transcription factor binding.
H2AFX and Non-Hodgkin Lymphoma
Previously unknown genes have been found through SAGE analysis in androgen independent prostate cancer.
Common regulators between autophagy and cell death
AR and β-catenin in androgen independent prostate cancer
Determination of optimal microarray designs
Rapid mapping of phenotypic traits
Macroautophagy: The key ingredient to a healthy diet?
Sintokamides A to E, chlorinated peptides from the sponge Dysidea sp. that inhibit transactivation of the N-terminus of the androgen receptor in prostate cancer cells.
Profiling model T cell metagenomes
cisRED C. elegans conserved element database
An executioner caspase regulates autophagy
Review of Massively Parallel MicroRNA Profiling in Cancer
Drosophila Genes Involved in Programmed Cell Death
Circos: An information aesthetic for comparative genomics.
The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution
Next generation tag sequencing for cancer gene expression profiling
Profiling the T-cell Receptor Beta-chain Repertoire by Massively Parallel Sequencing
Non-linear Electrophoretic Response Yields a New Parameter for Separation of Biomolecules
A quality management system application to investigate and troubleshoot process failures
Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver
Alternative expression analysis by RNA sequencing.
Moving the field of clinical genomics toward a future of more effective diagnosis and treatment of cancers.
Human T-cell repertoire analysis
Published July 27th in Nature
Concurrent CIC mutations, IDH mutations and 1p/19q loss distinguish oligodendrogliomas from other cancers.
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GSC’s 20th Anniversary: Celebrating with Science
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