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cisRED C. elegans conserved element database

Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements

We present the cisRED Caenorhabditis elegans database. We obtained orthologues for C. elegans protein-coding genes in seven other nematode species and identified conserved elements by de novo motif discovery. This catalogue of annotated conserved upstream elements can be used to find putative regulatory elements, discover novel RNA genes, understand the evolution of transcription factor binding sites, and identify novel binding site candidates for both characterized transcription factors in nematodes and orthologues of characterized mammalian transcription factors.

Sleumer MC, Bilenky M, He A, Robertson G, Thiessen N, Jones SJ. 2009 Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements. Nucleic Acids Res. 37(4):1323-34. [Epub 2009 Jan 16] PMID: 19151087 doi:10.1093/nar/gkn1041

 

For more information and to access the database go to the cisRed homepage

Page last modified Sep 17, 2009