Non-linear Electrophoretic Response Yields a New Parameter for Separation of Biomolecules
This paper was just accepted for publication in PNAS. It describes a novel and highly efficient electophoresis method for isolation and purification of DNA. The proof of principle application described in the paper was the isolation of DNA from a drilling core from the Athabasca oil sands, which was subsequently subjected to metagenomic sequencing and analysis here at the GSC.
Pel J, Broemeling D, Mai L, Poon H-L, Tropini G, Warren RL, Holt RA, Marziali A.
Non-linear Electrophoretic Response Yields a New Parameter for Separation of Biomolecules. Proceedings of the National Academy of Sciences of the United States of America. 2009 Aug 17. [Epub ahead of print]
PMID: 19706437 doi: 10.1073/pnas.0907402106
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Sep 17, 2009