Predicted mutational epitopes suitable for immunological cancer control
In this meta-analysis, scientists at the Genome Sciences Centre have evaluated all known somatic mutations in human tumors for their antigenic potential.
The approach consisted in quantifying somatic tumor mutations and any corresponding predicted, candidate epitopes that would be expected to be of utility in immunological cancer control. This allows, for the first time, estimation of the potential impact of preventative cancer vaccination.
Full citation
René L. Warren and Robert A. Holt. 2010. A census of predicted
mutational epitopes suitable for immunological cancer control. Human
Immunology. 10.1016/j.humimm.2009.12.007. 71:245-254
Further details of this publication can be found online.
Page last modified
Feb 25, 2010