Most Recent Peer Reviewed Publications
Mottok A, Hung SS, Chavez EA, Woolcock B, Telenius A, Chong LC, Meissner B, Nakamura H, Rushton C, Viganò E, Sarkozy C, Gascoyne RD, Connors JM, Ben Neriah S, Mungall A, Marra MA, Siebert R, Scott DW, Savage KJ, Steidl C. Integrative genomic analysis identifies key pathogenic mechanisms in primary mediastinal large B-cell lymphoma. Blood. 2019 Sep 5;134(10):802-813.
Karasinska JM, Topham JT, Kalloger S, Jang GH, Denroche RE, Culibrk L, Williamson LM, Wong HL, Lee MK, O'Kane GM, Moore RA, Mungall AJ, Moore MJ, Warren C, Metcalfe A, Notta F, Knox JJ, Gallinger S, Laskin JJ, Marra MA, Jones SJ, Renouf DJ, Schaeffer DF. Altered gene expression along the glycolysis-cholesterol synthesis axis is associated with outcome in pancreatic cancer. Clin Cancer Res. 2019 Sep 3. pii: clincanres.1543.2019. doi: 10.1158/1078-0432.CCR-19-1543. [Epub ahead of print]
Shen Y, Grisdale CJ, Islam SA, Bose P, Lever J, Zhao EY, Grinshtein N, Ma Y, Mungall AJ, Moore RA, Lun X, Senger DL, Robbins SM, Wang AY, MacIsaac JL, Kobor MS, Luchman HA, Weiss S, Chan JA, Blough MD, Kaplan DR, Cairncross JG, Marra MA, Jones SJM. Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments. Proc Natl Acad Sci U S A. 2019 Aug 30. pii: 201813495. doi: 10.1073/pnas.1813495116. [Epub ahead of print]
Wong D, Shen Y, Levine AB, Pleasance E, Jones M, Mungall K, Thiessen B, Toyota B, Laskin J, Jones SJM, Marra MA, Yip S. The pivotal role of sampling recurrent tumors in the precision care of patients with tumors of the central nervous system. Cold Spring Harb Mol Case Stud. 2019 Aug 1;5(4). pii: a004143. doi: 10.1101/mcs.a004143
Johnston M, Nikolic A, Ninkovic N, Guilhamon P, Cavalli F, Seaman S, Zemp F, Lee J, Abdelkareem A, Ellestad K, Murison A, Kushida M, Coutinho F, Ma Y, Mungall A, Moore R, Marra M, Taylor M, Dirks P, Pugh T, Morrissy S, St Croix B, Mahoney D, Lupien M, Gallo M. High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma. Genome Res. 2019 Aug;29(8):1211-1222.
Jones MR, Williamson LM, Topham JT, Lee MKC, Goytain A, Ho J, Denroche RE, Jang G-H, Pleasance ED, Shen Y, Karasinska JM, McGhie JP, Gill S, Lim H, Moore MJ, Wong H-L, Ng T, Yip S, Zhang W, Sadeghi S, Reisle CR, Mungall AJ, Mungall KL, Moore RA, Ma Y, Knox JJ, Gallinger S, Laskin J, Marra MA, Schaeffer DF, Jones SJM, Renouf DJ. NRG1 gene fusions are recurrent, clinically actionable gene rearrangements in KRAS wild-type pancreatic ductal adenocarcinoma. Clic Cancer Res. 2019 Aug 1;25(15):4674-4681.
Vladoiu M, El-Hamamy I, Donovan L, Farooq H, Holgado B, Ramaswamy V, Mack S, Lee J, Kumar S, Przelicki D, Michealraj KA, Juraschka K, Skowron P, Luu B, Suzuki H, Morrissy S, Cavalli F, Garzia L, Daniels C, Wu X, Qazi M, Singh S, Chan J, Marra M, Malkin D, Dirks P, Pugh T, Notta F, Kleinman C, Jabado N, Stein L, Taylor MD. Childhood Cerebellar Tumors Mirror Conserved Fetal Transcriptional Programs. Nature. 2019 Aug;572(7767):67-73.
Kwan HH, Culibrk L, Taylor GA, Leelakumari S, Tan R, Jackman SD, Tse K, MacLeod T, Cheng D, Chuah E, Kirk H, Pandoh P, Carlsen R, Zhao Y, Mungall AJ, Moore R, Birol I, Marra MA, Rosen DAS, Haulena M, Jones SJM. The Genome of the Steller Sea Lion (Eumetopias jubatus). Genes (Basel). 2019 Jun 26;10(7). pii: E486. doi: 10.3390/genes10070486.
Negri GL, Grande BM, Delaidelli A, El-Naggar A, Cochrane D, Lau CC, Triche TJ, Moore RA, Jones SJM, Montpetit A, Marra MA, Malkin D, Morin RD, Sorensen PH. Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma. J Pathol. 2019 Jun 24. doi: 10.1002/path.5319. [Epub ahead of print]
Feng X, Pleasance E, Zhao EY, Ng T, Grewal J, Mohammad N, Taylor SK, Simmons C, Srikanthan A, Rassekh, SR, Deyell R, Rauw R, Knowling M, Khoo K, Lee U, Noonan K, Hart J, Tonseth RP, Shen Y, Titmuss E, Jones M, Bonakdar M, Reisle C, Taylor GA, Chan S, Mungall R, Chuah E, Zhao YJ, Mungall A, Moore R, Lim H, Renouf DJ, Gelmon K, Yip S, Jones SJM, Marra M, Laskin J. Therapeutic implication of genomic landscape of adult metastatic sarcoma. JCO PO. 2019 Jun;3:1-25. doi: 10.1200/PO.18.00325.