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Scientific Publications

Publications starting from January 2012 and onwards. View older publications here.

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Recent Publications

2017/02/15

RNA-Seq Analysis of Gene Expression, Viral Pathogen, and B-Cell/T-Cell Receptor Signatures in Complex Chronic Disease.

Background. Chronic fatigue syndrome (CFS) remains poorly understood. Although infections are speculated to trigger the syndrome, a specific infectious agent and underlying pathophysiological mechani...

2017/02/11

Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.

Several studies have found that long-lived individuals do not appear to carry lower numbers of common disease-associated variants than ordinary people; it has been hypothesized that they may instead c...

2017/02/10

Kollector: transcript-informed, targeted de novo assembly of gene loci.

Motivation: Despite considerable advancements in sequencing and computing technologies, de novo assembly of whole eukaryotic genomes is still a time-consuming task that requires a significant amount o...

2017/02/06

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Several chronic lymphocytic leukaemia (CLL) susceptibility loci have been reported; however, much of the heritable risk remains unidentified. Here we perform a meta-analysis of six genome-wide associa...

2017/02/02

Genetic Polymorphism at BCL2 as a predictor for R-CHOP efficacy in patients with diffuse large B-cell lymphoma.

In this study, we examine the usefulness of germline BCL2 singlenucleotide polymorphisms (SNP) in identifying low and high risk patients. Our initial study identified two constitutional BCL2 SNPs sig...