Scientific Publications
Search results for "Moore RA"
2017/01/23
Integrated genomic and molecular characterization of cervical cancer.Cervical cancer remains one of the leading causes of cancer-related deaths worldwide. Here we report the extensive molecular characterization of 228 primary cervical cancers, the largest comprehensive...
2013/07/04
Comprehensive molecular characterization of clear cell renal cell carcinoma.Genetic changes underlying clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for exam...
2013/07/01
Complete genomic landscape of a recurring sporadic parathyroid carcinoma.Parathyroid carcinoma is a rare endocrine malignancy with an estimated incidence of less than 1 per million population. Excessive secretion of parathyroid hormone, extremely high serum calcium level, ...
2013/06/07
Complete genomic landscape of a recurring sporadic parathyroid carcinoma.Parathyroid carcinoma is a rare endocrine malignancy with an estimated incidence of less than 1 per million population. Excessive secretion of parathyroid hormone, extremely high serum calcium level, ...
2013/05/30
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.BACKGROUND: Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet c...
2013/05/22
Assembling the 20 Gb white spruce (Picea glauca) genome from whole-genome shotgun sequencing data.White spruce (Picea glauca) is a dominant conifer of the boreal forests of North America, and providing genomics resources for this commercially valuable tree will help improve forest management and c...
2013/04/01
The genetic landscape of high-risk neuroblastoma.Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease, resulting in survival rates of less than 50%. To determine the spectr...
2012/12/10
Derivation of HLA types from shotgun sequence datasets.ABSTRACT: The Human Leukocyte Antigen (HLA) is key to many aspects of human physiology and medicine. All current sequence-based HLA typing methodologies are targeted approaches requiring the amplifica...
2012/08/02
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As ...
2012/02/01
Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma.An estimated 15% or more of the cancer burden worldwide is attributable to known infectious agents. We screened colorectal carcinoma and matched normal tissue specimens using RNA-seq followed by host ...